Current member
Principal Investigator

Tianpeng Zhang, PhD
Principal Investigator
Assistant Professor
Department of Radiation Oncology
Department of Biochemistry & Molecular Genetics
University of Virginia School of Medicine
Member of UVA Comprehensive Cancer Center
Phone: 434-924-7479
Email: zjv8au@virginia.edu
Twitter/X: @zhtianp2
Tianpeng was born and raised in Hubei Province, China. Dr. Zhang received his B.A. (2012) and Ph.D. (2017) from the Sun Yat-Sen (Zhongshan) University, Guangzhou, China. In Dr. Yong Zhao's lab, he developed his interest in aging and carcinogenesis. He established novel methodologies to study telomere maintenance mechanisms, including resolution of telomere replication stress, regulation of telomere damage responses, and driving forces of Alternative Lengthening of Telomeres (ALT) mechanisms. In 2017, Tianpeng joined Dr. Roger Greenberg's lab at the School of Medicine of the University of Pennsylvania as a Postdoctoral Researcher. He continued his research interest in understanding the fundamental question of how ALT is initiated and maintained. In 2024, after the PhD and Postdoctoral training, Tianpeng established his independent research group at the Department of Radiation Oncology and Department of Biochemistry & Molecular Genetics, University of Virginia School of Medicine. Tianpeng is dedicated to studying genome integrity maintenance within repetitive sequences, and revealing their associated etiology and therapeutic vulnerabilities. Tianpeng received the Forbeck Scholar for William Guy Forbeck Research Foundation in 2019; AFCRI Funded Postdoctoral Fellowship from the University of Pennsylvania in 2022; and Trailblazers of Tomorrow National Postdoctoral Scholars from the University of Texas at Austin in 2024. Dr. Zhang's research is supported by UVASOM, UVACCC, and NIGMS-MIRA.
Postdoctoral Researcher

Dr. Chan is from Hong Kong. He earned his Bachelor’s degree in Forensic Science from Guangdong Medical University. In June 2024, he received his M.D. from Sun Yat-Sen University. His doctoral research focused on Oxaliplatin resistance in colorectal cancer (CRCs) when he was working in Dr. Xingding Zhang's lab. Dr. Chan demonstrated that the post-translational modification of proteins influenced CRC cell responsiveness to Oxaliplatin, particularly affecting the transcription factors involved in epithelial-mesenchymal transition (EMT) and glutamine-metabolizing enzymes. In October 2024, Dr. Chan joins Dr. Tianpeng Zhang’s lab at the Department of Radiation Oncology, University of Virginia School of Medicine, and focuses on epigenetic regulation of Alternative Lengthening of Telomeres.
Graduate Student

Kaicheng is from Suzhou, Jiangsu, China, a city renowned for its picturesque water town. He graduated from Nanjing University of Chinese Medicine in 2021 with a bachelor’s degree. Then he earned his master’s degree in 2024 from Fudan University, where he conducted research on the activation theory of miRNAs within cell nucleus. His work elucidated the functional diversities and underlying mechanisms of one pair of highly homologous miRNAs in non-small cell lung cancer (NSCLC). In December, Kaicheng joined Dr. Tianpeng Zhang’s lab at the University of Virginia, where his research focuses on the maintenance of centromere integrity. In July 2026, Kaicheng starts his graduate study at the BIMS program in UVASOM.
Undergraduate Students

Maya is from Ashburn, Virginia, and is a current undergraduate student at the University of Virginia. She wants to obtain a B.S. In Chemistry with a specialization in Biochemistry, as well as a minor in Women, Gender, and Sexuality. She is looking forward to learning new lab techniques, as well as learning about the relationship between repetitive sequences and diseases. In her free time, Maya enjoys knitting, crocheting, and playing video games.
Alumni
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Shibao Li, PhD,
Visiting Scholar (2025.01-2025.12)
Current: Affiliated Hospital of Xuzhou Medical University
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Brian J Diaz
Research Specialist (2024.09-2026.06)
Current: Advanced Microscopy Facility @ UVA
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Alexandra Wang
Undergraduate student (2024.09-2026.06)
Current: UVA Health
